Automated Microtiter Raman System

  • Automated Raman analysis of 96- and 384-well microtiter plates
  • Fast measurement of all wells within a few minutes
  • 785 nm Raman excitation for biotech and pharmaceutical applications
  • Spectral range 200-3500 cm-¹, resolution < 10 cm-¹
  • High throughput for screening and process development
  • Optional GMP 21 CFR Part 11 software
DWW

Dr. Wolf-Dieter Wagner

Laser, Quantum optics, Spectroscopy, Particle measurement


Fast screening of sample plates
High spectral resolution
Answer < 1 working day

Automated Microtiter Raman System MTRS-25002 for Laboratory Automation

The Automated Microtiter Raman System MTRS-25002 is a state-of-the-art, automated Raman analysis system for the rapid examination of samples in micro-well and microtiter plates. Specifically developed for demanding applications in biotechnology, pharmaceutical research, and process development, it enables the efficient analysis of large sample numbers through fully automated workflows.

Many biotechnological applications currently examine samples primarily using absorption or fluorescence measurements. However, these methods do not always provide sufficient molecular specificity. In contrast, Raman spectroscopy allows for direct molecular identification as well as detailed analysis of complex samples.

The Automated Microtiter Raman System MTRS-25002 also guarantees the rapid and reproducible acquisition of Raman spectra from microtiter plates. This enables significantly more efficient analysis in areas such as bioreactor screening, drug development, and general biotechnology research.

Precise automated Raman analysis of microtiter plates

The system offers numerous advantages for your workflow:

  • Versatility: The system is designed for standard 96- and 384-well microtiter plates and can automatically measure all wells of a plate with precision.
  • High-throughput This allows even large sample quantities to be analyzed in an extremely short time.
  • Signal Quality An integrated Raman spectrometer with high transmission ensures an excellent signal-to-noise ratio.
  • Speed Consequently, meaningful Raman spectra can be recorded even with short integration times of less than two seconds.
  • Data Management Automated functions such as background subtraction and database storage allow for efficient evaluation of measurement data and secure further processing for research.

Technical Highlights

  • Sample holder for 96- or 384-well microtiter plates

  • Automated Raman measurement of all wells within a few minutes

  • Raman excitation at 785 nm

  • High-transmission spectrometer with Resolution < 10 cm-¹

  • Spectral range 200 - 3500 cm-¹

  • Very good Signal-to-noise ratio with Integration times < 2 s

  • Automated background subtraction

  • Storage of the results in a large database

  • Optionally: GMP 21 CFR Part 11 Software for regulated applications

Typical applications

The automated microtiter Raman system is particularly suitable for applications with high sample throughputs, e.g:

  • Bioreactor screening

  • Biotechnological process development

  • Pharmaceutical research

  • High-throughput analysis of cell cultures

  • Molecular identification of complex samples

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